Blackened Salmon Sandwiches with Chipotle Mayo are a bold and flavorful twist on a classic seafood sandwich. Salmon fillets are coated in a smoky, spicy blackened seasoning and seared to perfection, creating a crispy exterior while remaining tender and juicy inside.

Layered on toasted sandwich buns with crisp lettuce, ripe tomatoes, and a smoky chipotle mayo, these sandwiches deliver a perfect balance of heat, freshness, and richness.

Why I Love This Recipe

I love this recipe because it’s quick, healthy, and packed with flavor. The blackened seasoning gives the salmon a smoky, spicy crust that contrasts beautifully with the creamy, smoky chipotle mayo and fresh vegetables. It’s a sandwich that feels indulgent yet nutritious.

Why This Is a Must-Try Dish

• Bold, smoky, and spicy flavors
• Quick and easy to prepare
• Healthy and protein-rich with omega-3s from salmon
• Perfect for lunch, dinner, or entertaining
• A creative, flavor-packed alternative to typical fish sandwiches

Preparation & Cooking Time

• Preparation Time: 10 minutes
• Cooking Time: 10–12 minutes
• Total Time: 20–22 minutes

Servings, Calories, Course & Cuisine

• Servings: 4 sandwiches
• Calories: ~450–500 calories per sandwich
• Course: Main Course / Sandwich
• Cuisine: American / Cajun-inspired

Ingredients

For the Salmon

• 4 salmon fillets (4–6 oz each), skin removed
• 1 tbsp smoked paprika
• 1 tsp garlic powder
• 1 tsp onion powder
• 1 tsp dried thyme
• ½ tsp cayenne pepper (adjust to taste)
• ½ tsp black pepper
• ½ tsp salt
• 2 tbsp olive oil

For the Chipotle Mayo

• ½ cup mayonnaise
• 1–2 chipotle peppers in adobo, finely minced
• 1 tsp lime juice
• Salt to taste

For the Sandwich

• 4 sandwich buns or brioche buns, lightly toasted
• 4 lettuce leaves
• 1 large tomato, sliced
• ¼ red onion, thinly sliced
• Optional: pickles or avocado slices

Cooking Directions

Make the Chipotle Mayo

1. In a small bowl, combine mayonnaise, minced chipotle peppers, lime juice, and a pinch of salt.
2. Mix well and refrigerate until ready to use.

Prepare the Salmon

1. In a small bowl, mix smoked paprika, garlic powder, onion powder, thyme, cayenne, black pepper, and salt.
2. Pat salmon fillets dry, then coat evenly with the spice mixture.

Cook the Salmon

1. Heat olive oil in a skillet over medium-high heat.
2. Place salmon fillets in the pan and cook 4–6 minutes per side, depending on thickness, until blackened and cooked through.

Assemble the Sandwich

1. Spread chipotle mayo on the top and bottom buns.
2. Layer lettuce, tomato slices, and red onion on the bottom bun.
3. Place the blackened salmon fillet on top.
4. Add any optional toppings, then cover with the top bun.

Step-by-Step Preparation Method

1. Prep salmon and spices: Mix blackened seasoning and coat salmon fillets.
2. Make chipotle mayo: Combine mayo, chipotle, lime juice, and salt; refrigerate.
3. Cook salmon: Heat oil in skillet, sear salmon 4–6 minutes per side until cooked through.
4. Toast buns: Lightly toast sandwich buns for extra crunch.
5. Assemble: Spread chipotle mayo, layer lettuce, tomato, onion, place salmon, top with bun.
6. Serve immediately for best flavor and texture.

How to Serve

Serve these sandwiches hot with a side of sweet potato fries, coleslaw, or a fresh green salad. A squeeze of lime over the top adds an extra burst of flavor.

Recipe Tips

• Pat salmon dry to ensure a good blackened crust.
• Adjust cayenne pepper in the spice rub for desired heat level.
• Make chipotle mayo a few hours ahead to let flavors meld.
• Use a non-stick or cast-iron skillet for perfect searing.
• Toasting the buns prevents sogginess from the mayo and tomato.

Variations

• Avocado Delight: Add sliced avocado for creaminess.
• Spicy Kick: Increase cayenne pepper or add hot sauce to the mayo.
• Asian Twist: Substitute chipotle mayo with sriracha mayo and top with pickled cucumbers.
• Salmon Salad Sandwich: Flake cooked salmon and mix with chipotle mayo for a shredded filling.
• Grilled Version: Grill salmon fillets outdoors for a smoky flavor.

Freezing & Storage

• Refrigerator: Store cooked salmon in an airtight container for up to 2 days; assemble sandwiches fresh.
• Freezing: Not recommended for fully assembled sandwiches; salmon can be frozen before cooking for up to 2 months. Thaw and cook as directed.

Special Equipment Needed

• Skillet (cast iron recommended)
• Small mixing bowl for mayo
• Knife and cutting board
• Spatula

Frequently Asked Questions

Q: Can I use salmon with skin on?
A: Yes, but adjust cooking time and sear skin-side first for crispiness.

Q: Can I make this sandwich ahead of time?
A: Assemble just before serving to maintain crispness of buns and freshness of toppings.

Q: Can I use store-bought blackened seasoning?
A: Absolutely, use your preferred pre-made blend for convenience.

Q: Can this recipe be made on a grill?
A: Yes, grill salmon fillets over medium-high heat for a smoky flavor.

Conclusion

Blackened Salmon Sandwiches with Chipotle Mayo are a flavorful, bold, and satisfying meal that combines the smoky heat of Cajun spices with the creamy, zesty chipotle mayo. Quick to prepare, healthy, and perfect for lunch or dinner, these sandwiches are a must-try for seafood lovers seeking a restaurant-quality meal at home.