Chicken and Spinach Lasagna Roll-Ups are a delightful twist on the traditional lasagna, offering all the cheesy, creamy, and savory flavors of the classic Italian comfort dish in a fun and elegant presentation. Instead of layering noodles in a pan, each noodle is filled with a rich mixture of shredded chicken, spinach, ricotta, and mozzarella, rolled up neatly, and baked in a luscious white or marinara sauce.

This dish is perfect for family dinners, gatherings, or even meal prep because it looks impressive yet is surprisingly easy to make. Each roll-up is portioned perfectly, making serving and storing effortless.

Why I Love This Recipe

I love this Chicken and Spinach Lasagna Roll-Up recipe because it combines the comforting richness of lasagna with the convenience of individual servings. Each roll is packed with a creamy, cheesy filling and topped with flavorful sauce — every bite feels like home.

Unlike traditional lasagna, there’s no fuss with multiple layers or uneven slices. It’s elegant, simple to serve, and perfect for both weeknights and special occasions. Plus, the chicken and spinach combo strikes a balance between indulgent and wholesome, giving you a protein-packed, veggie-rich meal in one bite.

Why It’s a Must-Try Dish

This dish is a must-try because:

• It’s beautifully portioned, ideal for family dinners or entertaining guests.
• Offers the classic lasagna flavor but with easier assembly and serving.
• The creamy chicken and spinach filling makes it lighter yet satisfying.
• You can make it ahead and freeze for busy days.
• The versatility — you can go white sauce or red sauce — keeps it exciting.

If you love lasagna but want a more manageable, elegant version, this recipe will win your heart instantly.

Recipe Details

• Preparation Time: 25 minutes
• Cooking Time: 35 minutes
• Total Time: 1 hour
• Servings: 6 servings (12 roll-ups)
• Calories: ~430 kcal per serving
• Course: Main Course
• Cuisine: Italian-American

Ingredients

For the Roll-Ups:

• 12 lasagna noodles
• 2 cups cooked shredded chicken (rotisserie or poached)
• 2 cups fresh spinach (or 1 cup frozen, thawed and drained)
• 1 ½ cups ricotta cheese
• 1 cup shredded mozzarella cheese (plus extra for topping)
• ¼ cup grated Parmesan cheese
• 1 egg, lightly beaten
• 1 tsp garlic powder
• 1 tsp Italian seasoning
• Salt and pepper, to taste

For the Sauce:

(You can use Alfredo or Marinara, depending on preference.)

White Sauce (Alfredo-style):

• 2 tbsp butter
• 2 tbsp all-purpose flour
• 2 cups milk
• ½ cup grated Parmesan cheese
• 1 clove garlic, minced
• Salt and pepper, to taste

Optional Garnish:

• Fresh basil or parsley
• Extra Parmesan for serving

Step-by-Step Preparation Method

Step 1: Cook the Lasagna Noodles

1. Bring a large pot of salted water to a boil.
2. Cook lasagna noodles according to package directions until al dente.
3. Drain and lay noodles flat on a baking sheet lined with parchment paper to prevent sticking.

Step 2: Prepare the Filling

1. In a large mixing bowl, combine shredded chicken, ricotta cheese, mozzarella, Parmesan, spinach, egg, garlic powder, Italian seasoning, salt, and pepper.
2. Stir until everything is well mixed and creamy.
3. Taste and adjust seasoning if necessary.

Step 3: Make the Sauce (if using white sauce)

1. In a saucepan, melt butter over medium heat.
2. Add flour and whisk constantly for about 1 minute to form a roux.
3. Slowly pour in milk, whisking until smooth and thickened (3–5 minutes).
4. Stir in Parmesan cheese, minced garlic, salt, and pepper.
5. Remove from heat and set aside.

Step 4: Assemble the Roll-Ups

1. Preheat oven to 375°F (190°C).
2. Spread a thin layer of sauce (white or marinara) on the bottom of a baking dish.
3. Lay one lasagna noodle flat on a clean surface.
4. Spread 2–3 tablespoons of filling evenly over it.
5. Roll the noodle up gently and place seam-side down in the baking dish.
6. Repeat with remaining noodles and filling.

Step 5: Top and Bake

1. Pour remaining sauce evenly over the roll-ups.
2. Sprinkle extra mozzarella and Parmesan on top.
3. Cover with foil and bake for 25 minutes.
4. Remove foil and bake uncovered for another 10 minutes until bubbly and golden.
5. Let rest for 5 minutes before serving.

How to Serve

Serve 2 roll-ups per person with:

• A side of garlic bread or Caesar salad
• A light drizzle of olive oil and sprinkle of Parmesan on top
• Garnish with fresh basil or parsley for a pop of color

It’s a complete, comforting meal that pairs beautifully with a glass of white wine or sparkling water with lemon.

Recipe Tips

• Use fresh or rotisserie chicken to save time.
• Don’t overfill the noodles — it makes rolling easier.
• Drain spinach well to prevent watery filling.
• Let them cool slightly before serving for cleaner slices.
• Add a pinch of nutmeg to the white sauce for depth.
• For a lighter version, use part-skim ricotta or low-fat mozzarella.

Variations

1. Marinara Chicken Roll-Ups:
   Use tomato-based marinara sauce instead of Alfredo for a tangier flavor.
2. Pesto Chicken Roll-Ups:
   Add 2 tablespoons of pesto to the filling or sauce for a fragrant twist.
3. Mushroom and Spinach Roll-Ups:
   Replace chicken with sautéed mushrooms for a vegetarian option.
4. Three-Cheese Roll-Ups:
   Skip the chicken and load up with ricotta, mozzarella, and fontina for extra cheesiness.
5. Spicy Alfredo Roll-Ups:
   Add red pepper flakes or a dash of hot sauce for a kick.

Freezing and Storage

Refrigeration:

• Store leftovers in an airtight container for up to 4 days.
• Reheat in the microwave or oven at 350°F (175°C) for 10–15 minutes.

Freezing (Before Baking):

• Assemble the roll-ups, cover tightly with foil, and freeze for up to 3 months.
• When ready to bake, thaw overnight in the fridge and bake as directed.

Freezing (After Baking):

• Let cool completely, portion, and freeze in containers for up to 2 months.

Special Equipment Needed

• Large pot (for boiling noodles)
• Mixing bowls
• Baking dish (9×13 inch)
• Whisk (for sauce)
• Spatula or spoon for spreading filling

Frequently Asked Questions (FAQ)

Q1: Can I use no-boil lasagna noodles?
Not recommended for roll-ups since they tend to crack — stick with regular noodles.

Q2: Can I make it ahead?
Yes! Assemble up to 24 hours in advance, refrigerate, and bake when ready.

Q3: Can I use canned chicken?
You can, but freshly cooked or rotisserie chicken has better flavor and texture.

Q4: Can I make it gluten-free?
Yes — use gluten-free lasagna noodles and substitute flour in the sauce with cornstarch.

Q5: Can I use frozen spinach?
Yes, just thaw and squeeze out all excess moisture before mixing it in.

Conclusion

Chicken and Spinach Lasagna Roll-Ups bring a fresh, modern take to the beloved classic. Creamy, cheesy, and comforting — they’re everything you want in a lasagna but in tidy, individual servings that look as good as they taste.

Whether you’re hosting a dinner party, meal-prepping for the week, or craving a wholesome, hearty meal, these roll-ups deliver on all fronts — flavor, simplicity, and satisfaction. It’s one of those recipes that makes the kitchen smell amazing and the table feel warm and inviting.