Prepare the Pork : Pat pork dry with paper towels. Season evenly with salt, pepper, paprika, garlic powder, and onion powder.
Slow Cook : Place pork in the crockpot. Whisk buffalo sauce, broth, melted butter, vinegar, and sugar. Pour sauce over pork. Cover and cook until pork is tender.
Shred and Finish : Remove pork and shred using two forks. Return shredded pork to crockpot and stir into sauce. Cook an additional 20–30 minutes to absorb flavor.