Make the Meatballs Preheat oven to 375°F (190°C). In a large bowl, combine ground meat, breadcrumbs, egg, onion, garlic, parsley, Parmesan, Italian seasoning, salt, and pepper. Mix until well combined, but don’t overwork the mixture. Shape into 12 equal meatballs. Heat olive oil in a skillet and sear the meatballs until browned on all sides (about 5 minutes). Transfer to a baking sheet and bake for 15–20 minutes, or until fully cooked (internal temp: 160°F / 71°C).